Postdoctoral Research Associate - Computational Systems Biology

Date: Apr 4, 2024

Location: Oak Ridge, TN, US, 37830

Company: Oak Ridge National Laboratory

Requisition Id 12465 



Oak Ridge National Laboratory is the largest US Department of Energy science and energy laboratory, conducting basic and applied research to deliver transformative solutions to compelling problems in energy and security.


We are seeking a Postdoctoral Research Associate who will support the Computational and Predictive Biology Group in the Biosciences Division (BSD), Biological and Environmental Systems Sciences (BESSD) at Oak Ridge National Laboratory (ORNL).  


The Biosciences Division is focused on advancing science and technology to better understand complex biological systems and their relationship with the environment. BSD has expertise and special facilities in genomics, computational systems biology, microbiology, microbial ecology, biophysics, and structural biology. Computational systems biology research includes methods development and use to analyze large scale omics, greenhouse, field, and clinical datasets to derive insights and hypotheses suitable for further experimental validation and to improve researchers’ ability to further advance understanding of biological systems.

We develop and apply computational methods to explore biological processes at all levels of life systems organization from atomistic to ecological scales. The collection of omics, phenotyping and environmental data, and automation of its analysis and discovery, is becoming increasingly important as the scale of experiments grow and diversify for projects at ORNL including the Center for Bioenergy Innovation, Plant Microbe Interfaces, Secure Ecosystem Engineering and Design, Integrated Pennycress Resilience projects, funded by the DOE, and Biomedical projects, funded by the NIH and VA, and pandemic prevention projects funded by the NSF and other government agencies, among other efforts that also include access to suitable large-scale computational resources.


In this position, you will be taking an important role in the development of approaches for systems biology, explainable-AI, network analysis, and information flow.


Major Duties/Responsibilities: 

  • Development and support of data collection, modeling, and integration, along with associated computational and machine/deep learning environments and interfaces for systems biology

  • Analyze large biological data sets to build accurate predictive models of biological processes and publish original work

  • Collaborate with internal and external researchers to analyze and interpret novel results using newly derived methods

  • Contribute to ongoing projects in the group and successfully define and develop their own projects


Basic Qualifications:

  • A PhD in computer science, computational biology, bioinformatics, systems biology, or a related field completed within the last 5 years

  • Strong computational science expertise, and a solid background in scientific programming, and computational techniques

  • Familiar with large-scale data analysis and understanding of data models to represent biological concepts

  • Excellent written and oral communication skills and the ability to communicate in English to a scientific audience

  • Familiarity with omics techniques such as RNA-seq, proteomics, metabolic profiling and genome resequencing and annotation is a plus


Further questions about this position should be directed to Daniel Jacobson (


Please submit three letters of reference when applying to this position. You can upload these directly to your application or have them sent to with the position title and number referenced in the subject line.


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  • Under the My Documents section, select Add a Document


Applicants cannot have received their Ph.D. more than five years prior to the date of application and must complete all degree requirements before starting their appointment. The appointment length will be for up to 24 months with the potential for extension. Initial appointments and extensions are subject to performance and the availability of funding.


Moving can be overwhelming and expensive. UT-Battelle offers a generous relocation package to ease the transition process. Domestic and international relocation assistance is available for certain positions. If invited to interview, be sure to ask your Recruiter (Talent Acquisition Partner) for details.

For more information about our benefits, working here, and living here, visit the “About” tab at


This position will remain open for a minimum of 5 days after which it will close when a qualified candidate is identified and/or hired.

We accept Word (.doc, .docx), Adobe (unsecured .pdf), Rich Text Format (.rtf), and HTML (.htm, .html) up to 5MB in size. Resumes from third party vendors will not be accepted; these resumes will be deleted and the candidates submitted will not be considered for employment.

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ORNL is an equal opportunity employer. All qualified applicants, including individuals with disabilities and protected veterans, are encouraged to apply.  UT-Battelle is an E-Verify employer.

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